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  1. Living and Dying with Dementia in England: Barriers to Care

    Living and Dying with Dementia in England: Barriers to Care

    REPORT / 2014 / There has been little focus on the inevitable conclusion of what is a progressive, terminal condition and there must be improvement in the care of people in the later stages of dementia. As it stands, the death and dying phase of dementia remains the forgotten aspect of what has been referred to as a 'silent epidemic'. Learn More

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    REP000827

    $2.00
  2. Top 100 Over 50s Housing Designs 2012

    Top 100 Over 50s Housing Designs 2012

    Compilation of the Top 100 Housing Designs for seniors form around the world. Comprising of Top 30 Designs from Australasia in 2012 (Retirement Villages, Independent Living, Nursing Homes, Dementia, Assisted Living), Top 30 Designs from UK in 2012 (Care Villages, Care Homes, Extra Care, Supported / Sheltered Housing, CCRC and Independent Living) and Top 40 Designs from USA in 2012 (Independent Living, Active Adult, CCRC, Assisted Living, Skilled Nursing, Dementia, Rental and Supported Housing) Learn More

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    RES000016

    $49.00
  3. Sequences Variation in SORL1 and Dementia Risk in Swedes

    Sequences Variation in SORL1 and Dementia Risk in Swedes

    Report/ 2010/ The gene encoding the neuronal sortilin-related receptor SORL1 has been claimed to be associated with Alzheimer?s disease (AD) by independent groups and across various human populations. This report evaluated six genetic markers in SORL1 in a sample of 1,558 Swedish dementia cases (including 1,270 AD cases) and 2,179 controls. Learn More

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    REP000319

    $5.00
  4. A Novel Variation in the Twinkle Linker Region Causing Late Onset Dementia

    A Novel Variation in the Twinkle Linker Region Causing Late Onset Dementia

    Report/ 2010/ Variations in the mitochondrial helicase Twinkle (PE01) gene are usually associated with autosomal dominant chronic progressive external opthalmoplegia (PEO). This study describes five patients from two unrelated Alsatian families with the new R374W variation in the Twinkle linker region who progressively developed an autosomal dominant multisystem disorder with PEO, hearing loss, myopathy, dysphagia, dysphonia, sensory neuropathy, and late-onset dementia resembling Alzheimer?s disease. These observations demonstrate that Twinkle variations in the linker domain alter cerebral function and further implicate disrupted mitochondrial DNA integrity in the pathogenesis of dementia. Learn More

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    REP000318

    $5.00
  5. Risk of Developing Dementia in People with Diabetes and Mild Cognitive Impairment

    Risk of Developing Dementia in People with Diabetes and Mild Cognitive Impairment

    Report/ 2011/ Background: Diabetes mellitus is associated with cognitive dysfunction, but it is not clear whether the disorder increases the risk of conversion from mild cognitive impairment to dementia. Conclusions: Diabetes mellitus increases not only the risks of dementia and mild cognitive impairment but also the risk of progression from such impairment to dementia. Learn More

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    REP000317

    $5.00
  6. Epidemiological Studies of the Effect of Stroke on Incident Dementia

    Epidemiological Studies of the Effect of Stroke on Incident Dementia

    Report/ 2011/ Up to half of all cases of dementia are thought to be caused wholly or in part by vascular disease in the brain, and stroke has long been implicated in dementia. This is historically reflected by the diagnoses of ?dementia with stroke? or ?multi-infarct dementia?, although these terms have been replaced with the broader concepts of vascular dementia and vascular cognitive impairment recognizing the contribution to dementia of all vascular disease. Pathological finding have shown that much dementia cannot be attributed to a singly underlying cause but arises from a combination of factors among which cerebrovascular disease, including infarct and hemorrhage, is an important contributor. Learn More

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    REP000316

    $5.00
  7. Use of Cerebrospinal Fluid Biomarkers in Diagnosis of Dementia Across Europe

    Use of Cerebrospinal Fluid Biomarkers in Diagnosis of Dementia Across Europe

    Report/ 2010/ Cerebrospinal fluid analysis of beta-amyloid, tau, and phosphorylated tau is frequently used in Europe. However, the use of various cut off values seriously hampers comparability and yields a potential threat to an interpretation and balanced use in clinical practice. The study recommends that each laboratory establishes normative data and that multi-centred studies should be organized to explore the reasons for any dfifferences. Learn More

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    REP000315

    $5.00
  8. Early Diagnosis of Dementia Based on Intersubject Whole Brain Dissimilarities

    Early Diagnosis of Dementia Based on Intersubject Whole Brain Dissimilarities

    Report/ 2010/ This article studies the possibility of detecting dementia in an early stage, using nonrigid registration of MR brain scans in combination with dissimilarity-based pattern recognition techniques. Instead of focusing on the shape of a single brains structure, taking into account the shape differences within the entire brain. Imaging data was obtained from a longitudinal, population based study of the elderly. Learn More

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    REP000314

    $5.00
  9. Evaluation of Dementia Rating Scales in Parkinson's Disease Dementia

    Evaluation of Dementia Rating Scales in Parkinson's Disease Dementia

    Report/ 2010/ Disease-specific assessments are not currently available for patients with Parkinson?s disease dementia (PDD). This study evaluated the criterion-related validity and test-retest reliability of the Alzheimer?s Disease Assessment scale cognitive subscale (ADAS-cog) in terms of sensitivity for differentiation between mild and moderate severity impairment in PDD. Six other dementia rating scales and cognitive tests were also examined. A total of 113 patients with PDD or Alzheimer disease were recruited into this 4-week, multicenter study, segregated into 2 severity groups based on Mini-Mental State Examination (MMSE) score. Learn More

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    REP000313

    $5.00
  10. Comorbid Depression is Associated with an Increased Risk of Dementia Diagnosis in Patients with Diabetes

    Comorbid Depression is Associated with an Increased Risk of Dementia Diagnosis in Patients with Diabetes

    Report/ 2010/ Patients with major depression and diabetes had an increased risk of development of dementia compared to those with diabetes alone. These data add to recent findings showing that depression was associated with an increased risk of macrovascular and microvascular complication in patients with diabetes. Learn More

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    REP000312

    $5.00

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